Shop GMC Sierra 2500HD Pickup Ignition Switch. Replace GMC Sierra 2500HD Pickup Ignition Replacement & GMC Sierra 2500HD Pickup Ignition System. Maintaining the ignition system in your GMC Sierra 2500HD Pickup is crucial for reliable performance. Regularly check and replace spark plugs and wires to prevent misfires and maintain fuel efficiency. If you experience engine stalling or difficulty starting, it's likely time for an ignition system overhaul. When selecting a new ignition, consider options like traditional coil packs or upgraded coil-on-plug systems, which offer improved combustion and longevity. Opt for high-quality materials to ensure durability, and for DIY enthusiasts, installation is straightforward with the right tools and manual. Keep your Sierra 2500HD running smoothly with these expert tips and curated ignition components, all available for a seamless online shopping experience.