Shop GMC Sierra 2500HD Pickup Driveline Replacement & GMC Sierra 2500HD Pickup Drivetrain. Explore GMC Sierra 2500HD Pickup Powertrain System. Maintaining the drivetrain of your GMC Sierra 2500HD Pickup ensures its robust performance and longevity. Regular checks of the differential fluid for cleanliness and proper levels can prevent premature wear, while listening for unusual noises or vibrations can signal the need for replacement components. When selecting a new drivetrain, consider the All-Wheel Drive (AWD) for enhanced traction or the Four-Wheel Drive (4WD) for superior off-road capability, each with high-quality materials designed for durability. Installation requires precision, so opt for professional fitting to guarantee optimal function and extend the lifespan of this crucial system. Shop our premium selection to enhance your GMC's drivetrain reliability and drive with confidence.